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Why Vitamins B, D, and Omega-3s Are the Health Trio You Need Now

June 2, 2025

Vitamin D3, B12 and Omega 3

Are You Missing the Top 3 Supplements Your Body Needs?

It started with a nagging sense of fatigue—then came brain fog, poor sleep, dry skin, and a noticeable drop in mood. These weren’t just signs of a busy life. They were symptoms of nutrient deficiencies, hiding in plain sight.

What most people don’t realize is how often these subtle signs are linked to low levels of vitamin B12, vitamin D, and Omega-3 fatty acids—three of the most common deficiencies in the U.S., even among health-conscious adults who exercise, hydrate, and eat relatively well.

You can drink green smoothies and log your steps religiously, but if your body is running low on these core nutrients, optimal health will always feel just out of reach.

The Hidden Toll of Vitamin Deficiencies

According to the Centers for Disease Control and Prevention (CDC), over 90% of Americans fall short on at least one essential nutrient. In an age where we have more access to food and information than ever before, this statistic is both surprising and alarming.

Let’s break it down:

  • Vitamin D deficiency affects approximately 42% of U.S. adults, particularly those who live in northern climates, have darker skin tones, or avoid sun exposure (Forrest & Stuhldreher, 2011). Even the most diligent sunscreen users are often vitamin D deficient.
  • Omega-3 fatty acid deficiency is even more widespread. A staggering 95% of Americans don’t get enough through their diet (Papanikolaou et al., 2014), largely due to low fish consumption and high intake of processed foods.
  • Vitamin B12 deficiency affects about 6% of people under 60 and nearly 20% over 60 (Allen, 2009). And many don’t even realize they’re running low until the symptoms become disruptive.

But this isn’t just about statistics. These deficiencies can quietly impact your:

  • Energy production
  • Mental clarity and memory
  • Immune resilience
  • Bone density
  • Mood and emotional regulation
  • Heart and metabolic health

Let’s take a closer look at each one—and what you can do to correct it.

B12: The Energy and Brain Support Powerhouse

If you’ve felt tired even after a full night’s sleep, or noticed tingling in your hands or feet, you could be low in vitamin B12. This essential nutrient plays a critical role in red blood cell formation, nervous system health, and DNA synthesis. Even mood disorders, irritability, and poor memory have been linked to low B12 levels.

One of the reasons B12 deficiency is so common is because its absorption depends on intrinsic factor, a compound produced in the stomach. As we age—or if we’re taking medications like metformin, proton pump inhibitors, or antacids—B12 absorption decreases significantly.

At Besana Health & Wellness in Lone Tree, we recommend weekly B12 injections for rapid and efficient replenishment, especially for those with chronic fatigue, anemia, or neurological symptoms. Injections bypass the digestive system entirely, delivering B12 directly to the bloodstream.

For those who prefer a high-quality oral supplement, Mitocore by Ortho Molecular is an excellent choice. It includes activated B vitamins (like methylcobalamin), antioxidants, and mitochondrial support for superior absorption and cellular energy production—unlike many drugstore multivitamins.

Vitamin D and K2: The Critical Combo for Bone and Heart Health

Vitamin D is best known as the “sunshine vitamin,” but its influence reaches far beyond mood and bones. It helps regulate over 200 genes, supports the immune system, improves calcium absorption, and may even reduce the risk of chronic conditions like heart disease, autoimmune disease, and depression.

But here’s something most people don’t know: Vitamin D should be taken with vitamin K2.

While D3 helps your body absorb calcium, K2 directs calcium to your bones and teeth—not your arteries or soft tissues. Without K2, there’s a risk of calcium buildup in places it doesn’t belong, which can increase the risk of cardiovascular disease.

That’s why we recommend a D3+K2 combination supplement, particularly in K2 MK-7 form, which is the most bioactive and longest-lasting version. It’s a small tweak with big consequences for your long-term health.  The majority of over-the-counter D3 supplements lack this synergy. By incorporating both in the proper ratio, Xymogen K2D3 5000 ensures you get not only adequate vitamin D but also the protection your heart and bones need. It’s a simple change that leads to better absorption, better results, and long-term wellness.

If you’ve been taking vitamin D but still feel achy, tired, or moody—or if you’ve had a blood test that shows normal calcium levels but low D—it’s time to re-evaluate your supplement strategy.

Omega-3s: The Anti-Inflammatory Essential

Joint pain, hormonal imbalances, dry skin, irritability, and brain fog can all point to low levels of Omega-3 fatty acids. These essential fats—EPA and DHA—can’t be made by the body and must come from diet or supplements.

The real issue? The standard American diet is excessively high in Omega-6 fatty acids, which fuel inflammation. This imbalance makes it almost impossible to get the full benefits of Omega-3s, even if you’re eating fish once or twice a week.

We recommend Xymogen’s Monopure, a professional-grade Omega-3 supplement that stands out from the crowd. It’s:

  • Enteric-coated to eliminate fishy aftertaste
  • Highly purified and tested for mercury and PCBs
  • Pharmaceutical-grade, meaning every dose is effective and safe
  • Shown to support triglyceride reduction, brain health, and inflammation control

Unlike low-cost fish oil capsules that can oxidize (go rancid) on store shelves, Monopure delivers what your body actually needs—without the unwanted side effects.

How Besana Health & Wellness in Lone Tree Can Help

At Besana Health & Wellness, we don’t believe in guesswork. Our team uses comprehensive nutrient testing to assess your individual needs and uncover hidden deficiencies that could be affecting your day-to-day life.

Through personalized supplement protocols and access to therapeutic-grade formulations, we help patients restore optimal levels and feel like themselves again—often within just weeks. Whether you’re struggling with fatigue, mood swings, brain fog, or are simply committed to aging vibrantly, B12, D3+K2, and Omega-3s are the foundation.

You don’t have to navigate your supplement journey alone or rely on over-the-counter guesses. At Besana, we blend advanced testing, clinical expertise, and natural therapies to help you reach your health goals.

When it comes to your health, guessing isn’t a strategy. Testing, correcting, and optimizing your nutrient levels can transform how you feel, think, and function—day in and day out.

So, if you’ve been feeling off without a clear reason, or suspect you might be missing something, these three nutrients—vitamin B12, vitamin D with K2, and Omega-3s—are the place to start.

Are you ready to take control of your health and discover which nutrients your body is really missing?

 

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    BESANA Health & Wellness is a partner practice with Atagi Plastic Surgery. After 18 successful years of serving her plastic surgery patients, Dr. Atagi founded BESANA to empower her patients to live their fullest lives, providing a holistic and preventive approach to wellness in a culture of community.

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